Direct Meds vs Willow: Price, Yearly Cost & Cancellation
On the most flexible semaglutide plans, Direct Meds costs $24 less over a year ($3,564 vs $3,588). On the most flexible tirzepatide plans, both cost $4,788 a year. Direct Meds charges no membership fee; Willow charges no membership fee. Prices verified September 24, 2026.
Side by side
| Direct Meds | Willow | |
|---|---|---|
| Semaglutide, most flexible plan | $297/mo (90-day supply, 3-month commitment) | $299/mo |
| Tirzepatide, most flexible plan | $399/mo (90-day supply, 3-month commitment) | $399/mo |
| Semaglutide, lowest rate | $249/mo (not stated) | $299/mo (monthly subscription) |
| Tirzepatide, lowest rate | $399/mo (90-day supply, 3-month commitment) | $399/mo (monthly subscription) |
| Semaglutide, first year | $3,564 | $3,588 |
| Tirzepatide, first year | $4,788 | $4,788 |
| Membership fee | None | None |
| Higher doses | Not stated. | Possible: terms say the Subscription Fee may be increased or decreased if the prescription changes, 'such as by a dosage increase', with disclosure and consent before charging. |
| Consultation | Async online intake/quiz reviewed by a licensed provider (FAQ: no appointments needed). | Online assessment reviewed by physicians of Willow's affiliated medical practice; same-day prescriptions advertised; unlimited physician access and 24/7 care team. Visit format not specified. |
| States | Not published | Not published |
| How to cancel | Turn off auto-refill in the account portal at least 48 hours before the next processing date (terms), or email help@direct-meds.com / call (888) 696-7176 (product pages). | FAQ: message the Patient Care Team; terms: log into the account page at StartWillow.com. |
| Refunds | Orders can be cancelled within 24 hours if not yet with the provider network; after that generally not. No refunds for medication already received. Full refund if the doctor declines treatment. Advance notice 5-7 days before each charge. | Full refund within 5-10 business days if canceled before the prescription is sent to the pharmacy; otherwise charges are non-refundable once incurred (per terms, subject to the Subscription and Return Policies). |
| Trustpilot | 4.6 (15,693 reviews) | 3.9 (356 reviews) |
| Regulatory notes | FDA warning letter dated Sept 9, 2025 (posted Sept 16, 2025) to directmeds.com, Inc | Eli Lilly sued Willow Health Services (April 2025) alleging false claims about compounded tirzepatide, including marketing a 'cosmetic' GLP-1; a federal judge dismissed the suit in September 2025, finding Lilly had not shown patients or physicians switched to the compounded product.; News coverage of the Lilly lawsuit naming Willow Health. |
First-year cost uses each provider's most flexible plan (month-to-month where offered), including any intro month and membership fee. Prepaid plans cost less per month but are harder to exit.
Choose Direct Meds if…
- you want the lower yearly cost for semaglutide ($3,564 vs $3,588 on their most flexible plans)
- you're willing to prepay for the lowest semaglutide rate ($249/mo on its not stated plan)
- a higher Trustpilot score matters to you (4.6 vs 3.9)
- you prefer a provider with fewer regulatory notes on record
Choose Willow if…
Neither provider clearly wins on the points we compare — check the table.
Full reviews
Other comparisons
FAQ
Is Direct Meds or Willow cheaper for semaglutide?
Direct Meds is cheaper on its most flexible plan: $3,564 for the first year vs $3,588, based on prices verified September 24, 2026.
Is Direct Meds or Willow cheaper for tirzepatide?
They cost the same on their most flexible plans: $4,788 for the first year.
Do Direct Meds or Willow charge a membership fee?
Direct Meds: None. Willow: None.
Which has better reviews, Direct Meds or Willow?
On Trustpilot, Direct Meds has 4.6 (15,693 reviews) and Willow has 3.9 (356 reviews).
Sources
- Direct Meds: Homepage
- Direct Meds: Weight-loss page + FAQ
- Direct Meds: Semaglutide injection product page
- Willow: Homepage
- Willow: Compounded semaglutide
- Willow: Compounded tirzepatide
- Full source lists: Direct Meds, Willow
Compounded medications are not FDA-approved finished drug products. This page is not medical advice.