MyStart Health vs TrimRx: Price, Yearly Cost & Cancellation
On the most flexible semaglutide plans, TrimRx costs $100 less over a year ($3,488 vs $3,588). On the most flexible tirzepatide plans, MyStart Health costs $1,150 less over a year ($3,588 vs $4,738). MyStart Health charges no membership fee; TrimRx charges no membership fee. Prices verified October 16, 2026.
Side by side
| MyStart Health | TrimRx | |
|---|---|---|
| Semaglutide, most flexible plan | $299/mo | $299/mo (first month $199) |
| Tirzepatide, most flexible plan | $299/mo | $399/mo (first month $349) |
| Semaglutide, lowest rate | $299/mo (monthly (4-week supply) or 3-month (12-week supply) plan) | $299/mo (monthly) |
| Tirzepatide, lowest rate | $299/mo (monthly (4-week supply) or 3-month (12-week supply) plan) | $399/mo (monthly) |
| Semaglutide, first year | $3,588 | $3,488 |
| Tirzepatide, first year | $3,588 | $4,738 |
| Membership fee | None | None |
| Higher doses | None per FAQ price-lock ('will never increase from your base plan amount, EVEN if your dosage increases'); first-time discount excluded. | None: homepage says 'Guaranteed Pricing', cost stays the same as the dose changes. |
| Consultation | Online intake quiz reviewed by a licensed clinician; video consult or prescription within 24 hours, same-day video available. Unlimited clinician messaging at no added cost; refill intake form required every 3 months. | Async online assessment reviewed by a provider; a short telehealth call is arranged if needed or if state rules require it. |
| States | All 50 states | All 50 states |
| How to cancel | Email support with 'CANCEL' in the subject line, or call 888-828-5816 (Mon-Fri 9am-7pm, Sat 10am-4pm ET). | Through the TrimRx account, chat, or phone 888-896-1612 (support 7 days, 6am-6pm PT). |
| Refunds | Full refund if not medically eligible or if canceled before the pharmacy processes and ships the order. No refunds once shipped or once a prescription is written, and none for completed or partially completed membership periods; medication cannot be returned. | Full refund if medically disqualified or for billing errors. Orders already sent to the pharmacy still ship. Unused prepaid multi-month portions are refundable only if requested within 28 days of payment (email hello@trimrx.com). Refund available if medication hasn't shipped within 14 days of the order. |
| Trustpilot | 4.1 (326 reviews) | 3.7 (5,419 reviews) |
| Regulatory notes | FDA warning letter to MyStart Health LLC (Sept 9, 2025) for false or misleading claims about compounded semaglutide, including 'Generic brand-name semaglutide' wording that implied equivalence to FDA-approved drugs. | BBB investigated TrimRx in March 2026 over complaints of charging/shipping before medical approval, charging multi-month amounts instead of the chosen monthly plan, not honoring cancellations, undisclosed fees, and slow responses; BBB also challenged several advertising claims. |
First-year cost uses each provider's most flexible plan (month-to-month where offered), including any intro month and membership fee. Prepaid plans cost less per month but are harder to exit.
Choose MyStart Health if…
- you want the lower yearly cost for tirzepatide ($3,588 vs $4,738 on their most flexible plans)
- you're willing to prepay for the lowest tirzepatide rate ($299/mo on its monthly (4-week supply) or 3-month (12-week supply) plan plan)
- a higher Trustpilot score matters to you (4.1 vs 3.7)
Choose TrimRx if…
- you want the lower yearly cost for semaglutide ($3,488 vs $3,588 on their most flexible plans)
Full reviews
Other comparisons
FAQ
Is MyStart Health or TrimRx cheaper for semaglutide?
TrimRx is cheaper on its most flexible plan: $3,488 for the first year vs $3,588, based on prices verified October 16, 2026.
Is MyStart Health or TrimRx cheaper for tirzepatide?
MyStart Health is cheaper on its most flexible plan: $3,588 for the first year vs $4,738, based on prices verified October 16, 2026.
Do MyStart Health or TrimRx charge a membership fee?
MyStart Health: None. TrimRx: None.
Which has better reviews, MyStart Health or TrimRx?
On Trustpilot, MyStart Health has 4.1 (326 reviews) and TrimRx has 3.7 (5,419 reviews).
Sources
- MyStart Health: Homepage FAQ (price, cancellation, price-lock)
- MyStart Health: Support FAQs
- MyStart Health: Refund policy
- TrimRx: Homepage (starting prices, guaranteed pricing)
- TrimRx: FAQs (cancellation, support hours)
- TrimRx: Terms and conditions (prices, refunds, states, payments)
- Full source lists: MyStart Health, TrimRx
Compounded medications are not FDA-approved finished drug products. This page is not medical advice.